Table of Contents

Review

2. The Venus Flytrap of Periplasmic Binding Proteins: An Ancient Protein Module Present in Multiple Drug Receptors.
Christian Felder, Richard Graul, Alan Lee, Hans Merkle, Wolfgang Sadee

Editorial

At the Crossroads of Publishing: An Introduction to AAPS PharmSci
Wolfgang Sadee

Original Research Articles

1. Glycylsarcosine Uptake in Rabbit Renal Brush Border Membrane Vesicles Isolated From Outer Cortex or Outer Medulla: Evidence for Heterogeneous Distribution of Oligopeptide Transporters
Chun-Jung Lin, David Smith

3. Prediction of Dissolution-Absorption Relationships from a Continuous Dissolution/Caco-2 System
Mark Ginski, Rajneesh Taneja, James Polli

4. Design and Synthesis of the CB1 Selective Cannabinoid Antagonist AM281: A Potential Human SPECT Ligand
Ruoxi Lan, John Gatley, Qian Liu, Pusheng Fan, Susanthi Fernando, Nora Volkow, Roger Pertwee, Alexandros Makriyannis

6. A Method To Monitor DNA Transfer During Transfection
Andrew Johnson, Joseph Jurcisek, O. Trask, Jessie Au

Meeting Report

5. Second AAPS-NIH Frontier Symposium 1999: Membrane Transporters and Drug Therapy
David Pang, Gordon Amidon, Peter Preusch, Wolfgang Sadee