Scientific Journals: AAPS PharmSci


30. Role of Plasma Lipoproteins in Modifying the Toxic Effects of Water-Insoluble Drugs: Studies With Cyclosporine A
Kishor M Wasan, Manisha Ramaswamy, Mona Kwong and Kathy D Boulanger

29. Detection of MDR1 Single Nucleotide Polymorphisms C3435T and G2677T Using Real-Time Polymerase Chain Reaction: MDR1 Single Nucleotide Polymorphism Genotyping Assay
Pengfei Song, Shen Li, Bernd Meibohm, A Osama Gaber, Marsha R Honaker, Malak Kotb and Charles R Yates

28. Effects of Obesity on the Pharmacodynamics of Nitroglycerin in Conscious Rats
Ellen Q Wang and Ho-Leung Fung

27. Comparison of Stepwise Covariate Model Building Strategies in Population Pharmacokinetic-Pharmacodynamic Analysis
Ulrika Wahlby, E Niclas Jonsson and Mats O Karlsson

26. Peptide Delivery to the Brain via Adsorptive-Mediated Endocytosis: Advances With SynB Vectors
Guillaume Drin, Christophe Rousselle, Jean-Michel Scherrmann, Anthony R Rees and Jamal Temsamani

25. Which Concentration of the Inhibitor Should Be Used to Predict In Vivo Drug Interactions From In Vitro Data?
Kiyomi Ito, Koji Chiba, Masato Horikawa, Michi Ishigami, Naomi Mizuno, Jun Aoki, Yasumasa Gotoh, Takafumi Iwatsubo, Shin-ichi Kanamitsu, Motohiro Kato, Iichiro Kawahara, Kayoko Niinuma, Akiko Nishino, Norihito Sato, Yuko Tsukamoto, Kaoru Ueda, Tomoo Itoh and Yuichi Sugiyama

24. Pharmacokinetics, Mass Balance, and Tissue Distribution of a Novel DNA Alkylating Agent, VNP40101M, in Rats
John Mao, Yang Xu, Diana Wu and Bijan Almassain

23. Bioinformatic Analysis of the Human µ Opioid Receptor (OPRM1) Splice and Polymorphic Variants
Lili Xin and Zaijie Jim Wang

22. Population Analysis of the Pharmacokinetics and Pharmacodynamics of RWJ-270201 (BCX-1812) in Treating Experimental Influenza A and B Virus in Healthy Volunteers
Ganesh R Iyer, Sam Liao and Joseph Massarella

21. Monitoring Intracellular pH Changes in Response to Osmotic Stress and Membrane Transport Activity Using 5-Chloromethylfluorescein
Aline Salvi, J Mark Quillan and Wolfgang Sadee

20. Bioerodible Injectable Poly(ortho ester) for Tetracycline Controlled Delivery to Periodontal Pockets: Preliminary Trial in Humans
K Schwach-Abdellaoui, PJ Loup, N Vivien-Castioni, A Mombelli, P Baehni, J Barr, J Heller and R Gurny

19. Preformulation Development of Recombinant Pegylated Staphylokinase SY161 Using Statistical Design
Frank Bedu-Addo, Randall Moreadith and Siddharth J. Advant

18. Model System to Study Classical Nuclear Export Signals
Charu Kanwal, Henan Li and Carol S. Lim

17. Comparison of the Formulation Requirements of Dosator and Dosing Disc Automatic Capsule Filling Machines
Pavan K. Heda, Kapiamba Muteba and Larry L. Augsburger

16. The Effect of AlkylpolyglycosideSurfactants on the Crystallization of Spray-Dried Salbutamol Sulphate: a GravimetricNear-Infrared Spectroscopy Study
Angela Columbano, Graham Buckton and Philip Wikeley

15. Cloning and Characterization of the Rat Multidrug Resistance-Associated Protein 1
Ziping Yang, Cheryl Li, Danny Shen and Rodney Ho

14. Role of MRP4 and MRP5 in Biology and Chemotherapy
Janardhan Sampath, Masashi Adachi, Sigrid Hatse, Lieve Naesens, Jan Balzarini, Robin Flatley, Larry Matherly and John Schuetz

13. Aerosolization of Lipoplexes Using AERx® Pulmonary Delivery System
Deepa Deshpande, James Blanchard, Sudarshan Srinivasan, Dallas Fairbanks, Jun Fujimoto, Teiji Sawa, Jeanine Wiener-Kronish, Hans Schreier and Igor Gonda

12. Transfection Efficiency and Toxicity of Polyethylenimine in Differentiated Calu-3 and Nondifferentiated COS-1 Cell Cultures
Bogdan I. Florea, Clare Meaney, Hans E. Junginger and Gerrit Borchard

11. Influence of Fluoxetine on Olanzapine Pharmacokinetics
Denis Gossen, Jean-Marie de Suray, Francois Vandenhende, Claude Onkelinx and Diamon Gangji

10. cDNA Microarray Analysis of Vascular Gene Expression After Nitric Oxide Donor Infusions in Rats: Implications for Nitrate Tolerance Mechanisms
Ellen Q. Wang, Woo-In Lee, Daniel Brazeau and Ho-Leung Fung

9. Is Antisense an Appropriate Nomenclature or Design for Oligodeoxynucleotides Aimed at the Inhibition of HIV-1 Replication?
Carole Lavigne, Jocelyn Yelle, Gilles Sauve, and Alain R. Thierry

8. Pharmacologic and Pharmacokinetic Profile of Repifermin (KGF-2) in Monkeys and Comparative Pharmacokinetics in Humans
Cynthia Sung, Tom J. Parry, Todd A. Riccobene, Angela Mahoney, Viktor Roschke, James Murray, Mi Li Gu, Jeffrey K. Glenn, Florence Caputo, Cindy Farman and Daniel J. Odenheimer

7. Assuring Quality and Performance of Sustained and Controlled Release Parenterals: Workshop Report
Diane J. Burgess, Ajaz S. Hussain, Thomas S. Ingallinera and Mei-Ling Chen

6. Novel System to Investigate the Effects of Inhaled Volume and Rates of Rise in Simulated Inspiratory Air Flow on Fine Particle Output From a Dry Powder Inhaler
Varsha Chavan and Richard Dalby

5. Pharmacogenomics: The Implementation Phase
Wolfgang Sadee

4. Protein Binding Predictions in Infants
Patrick J. McNamara and Jane Alcorn

3. Application of Confocal Laser Scanning Microscopy in Characterization of Chemical Enhancers in Drug-in-Adhesive Transdermal Patches
Michael H. Qvist, Ulla Hoeck, Bo Kreilgaard, Flemming Madsen, Lars Hovgaard, and Sven Frokjaer

2. Ocular Tolerance of Absorption Enhancers in Ophthalmic Preparations
Pascal Furrer, Joachim Michael Mayer, Bernard Plazonnet and Robert Gurny


1. Evaluation of USP Apparatus 3 for Dissolution Testing of Immediate-Release Products
Lawrence X. Yu, Jin T. Wang and Ajaz S. Hussain


34. Delivery of Antibiotics to the Eye Using a Positively Charged Polysaccharide as Vehicle
O. Felt, V. Baeyens, P. Buri and R. Gurny


33. A National Survey of U.S. Pharmacists in 2000: Assessing Nonresponse Bias of a Survey Methodology
David A. Mott, Craig A. Pedersen, William R. Doucette, Caroline A. Gaither and Jon C. Schommer


32. The Cytoplasmic Escape and Nuclear Accumulation of Endocytosed and Microinjected HPMA Copolymers and a Basic Kinetic Study in Hep G2 Cells
Keith D. Jensen, Pavla Kopeckova, John H.B. Bridge and Jindrich Kopecek


31. Single Nucleotide Polymorphisms of the Human M1 Muscarinic Acetylcholine Receptor Gene
Julie L. Lucas, Joseph A. DeYoung and Wolfgang Sadee

30. Receptor Binding Studies of Soft Anticholinergic Agents
Fenglei Huang, Peter Buchwald, Clinton E. Browne, Hassan H. Farag, Whei-Mei Wu, Fubao Ji, Guenther Hochhaus and Nicholas Bodor

29. Allometric Scaling of Xenobiotic Clearance: Uncertainty versus Universality
Teh-Min Hu and William L. Hayton

28. Electronic and Resonance Effects on the Ionization of Structural Analogues of Efavirenz
Shelly R. Rabel, Mona Patel, Sophie Sun and Michael B. Maurin

27. Skeletal Effects of Parathyroid Hormone (1-34) in Ovariectomized Rats With or Without Concurrent Administration of Salmon Calcitonin
Patrick P. DeLuca and Bhas A. Dani

26. Selected Physical and Chemical Properties of Commercial Hypericum perforatum Extracts Relevant for Formulated Product Quality and Performance
Susan H. Kopleman, Agnes NguyenPho, William S. Zito, Fran X. Muller and Larry L. Augsburger

25. Comparison of the Gravimetric, Phenol Red, and 14C-PEG-3350 Methods to Determine Water Absorption in the Rat Single-Pass Intestinal Perfusion Model
Steven C. Sutton, M.T.S. Rinaldi and K.E. Vukovinsky

24. Influence of Drug Release Properties of Conventional Solid Dosage Forms on the Systemic Exposure of Highly Soluble Drugs
Lawrence X. Yu, Christopher D. Ellison, Dale P. Conner, Larry J. Lesko and Ajaz S. Hussain

23. Use of FT-NIR Transmission Spectroscopy for the Quantitative Analysis of an Active Ingredient in a Translucent Pharmaceutical Topical Gel Formulation
Mark S. Kemper, Edgar J. Magnuson, Stephen R. Lowry, William J. McCarthy, Napasinee Aksornkoae, D. Christopher Watts, James R. Johnson and Atul J. Shukla

22. Genetic Variations in Human G Protein-Coupled Receptors: Implications for Drug Therapy
Wolfgang Sadee, Elen Hoeg, Julie Lucas and Danxin Wang

21. DNA/polyethylenimine transfection particles: Influence of ligands, polymer size, and PEGylation on internalization and gene expression
Manfred Ogris, Peter Steinlein, Sebastian Carotta, Sylvia Brunner and Ernst Wagner

20. Comparative Evaluation of Tableting Compression Behaviors by Methods of Internal and External Lubricant Addition: Inhibition of Enzymatic Activity of Trypsin Preparation by Using External Lubricant Addition During the Tableting Compression Process
Makoto Otsuka, Mitsuyo Sato and Yoshihisa Matsuda

19. Low Molecular Weight Protamine as Nontoxic Heparin/Low Molecular Weight Heparin Antidote (III): Preliminary In Vivo Evaluation of Efficacy and Toxicity Using a Canine Model
Lai Ming Lee, Li-Chien Chang, Shirley Wrobleski, Thomas W. Wakefield, and Victor C. Yang

18.Low Molecular Weight Protamine (LMWP)as Nontoxic Heparin/Low Molecular Weight Heparin Antidote (II): In Vitro Evaluation of Efficacy and Toxicity
Li-Chien Chang, Jun Feng Liang, Hsiao-Feng Lee, Lai Ming Lee, and Victor C. Yang

17. Low Molecular Weight Protamine (LMWP) as Nontoxic Heparin/Low Molecular Weight Heparin Antidote (I): Preparation and Characterization
Li-Chien Chang, Hsiao-Feng Lee, ZhiQiang Yang, and Victor C. Yang

16. Three-Dimensional Structure of Fibrolase, the Fibrinolytic Enzyme from Southern Copperhead Venom, Modeled from the X-Ray Structure of Adamalysin II and Atrolysin C

Michael B. Bolger, Steve Swenson, and Francis S. Markland, Jr.

 

 

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