Kulkarni SG, Pegram AA and Smith PC Disposition of Acetaminophen and Indocyanine Green in Cystic Fibrosis-Knockout Mice AAPS PharmSci 2000;
2
(2)
article 18
(https://www.pharmsci.org/scientificjournals/pharmsci/journal/18.html).
Figures and Tables
Figure 1.Representative plasma concentration time profile of acetaminophen (APAP) (filled
diamond) and its glucuronide (open square) and sulfate (open triangle)
metabolites in a cystic fibrosis (-/-) male mouse administered APAP (50 mg/kg,
ip).
Table 1.
Pharmacokinetic Parameters for APAP and Its
Conjugated Metabolites in Male CF Mice After 50 mg/kg Intraperatoneal
Administration*
(Click here to view table)
Table 2.
Pharmacokinetics of APAP and its Conjugated Metabolites in Female CF Mice After 50 mg/kg Intraperitoneal Administration
(Click here to view table)
Figure 2.
Representative plasma concentration time profiles of indocyanine green (ICG) in
cystic fibrosis +/- (open triangle) and -/- (filled diamond) male mice injected
with ICG (10 mg/kg, iv) via the tail vein.
Table 3.
Pharmacokinetic Parameters for ICG in Male and Female CF Mice After a 10-mg/kg Intravenous Bolus*
(Click here to view table)
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