
30. Role of Plasma Lipoproteins in Modifying the Toxic Effects of Water-Insoluble Drugs: Studies With Cyclosporine A Kishor M Wasan, Manisha Ramaswamy, Mona Kwong and Kathy D Boulanger
29. Detection of MDR1 Single Nucleotide Polymorphisms C3435T and G2677T Using Real-Time Polymerase Chain Reaction: MDR1 Single Nucleotide Polymorphism Genotyping Assay Pengfei Song, Shen Li, Bernd Meibohm, A Osama Gaber, Marsha R Honaker, Malak Kotb and Charles R Yates
28. Effects of Obesity on the Pharmacodynamics of Nitroglycerin in Conscious Rats Ellen Q Wang and Ho-Leung Fung
27. Comparison of Stepwise Covariate Model Building Strategies in Population Pharmacokinetic-Pharmacodynamic Analysis Ulrika Wahlby, E Niclas Jonsson and Mats O Karlsson
26. Peptide Delivery to the Brain via Adsorptive-Mediated Endocytosis: Advances With SynB Vectors Guillaume Drin, Christophe Rousselle, Jean-Michel Scherrmann, Anthony R Rees and Jamal Temsamani
25. Which Concentration of the Inhibitor Should Be Used to Predict In Vivo Drug Interactions From In Vitro Data? Kiyomi Ito, Koji Chiba, Masato Horikawa, Michi Ishigami, Naomi Mizuno, Jun Aoki, Yasumasa Gotoh, Takafumi Iwatsubo, Shin-ichi Kanamitsu, Motohiro Kato, Iichiro Kawahara, Kayoko Niinuma, Akiko Nishino, Norihito Sato, Yuko Tsukamoto, Kaoru Ueda, Tomoo Itoh and Yuichi Sugiyama
24. Pharmacokinetics, Mass Balance, and Tissue Distribution of a Novel DNA Alkylating Agent, VNP40101M, in Rats John Mao, Yang Xu, Diana Wu and Bijan Almassain
23. Bioinformatic Analysis of the Human µ Opioid Receptor (OPRM1) Splice and Polymorphic Variants Lili Xin and Zaijie Jim Wang
22. Population Analysis of the Pharmacokinetics and Pharmacodynamics of RWJ-270201 (BCX-1812) in Treating Experimental Influenza A and B Virus in Healthy Volunteers Ganesh R Iyer, Sam Liao and Joseph Massarella
21. Monitoring Intracellular pH Changes in Response to Osmotic Stress and Membrane Transport Activity Using 5-Chloromethylfluorescein Aline Salvi, J Mark Quillan and Wolfgang Sadee
20. Bioerodible Injectable Poly(ortho ester) for Tetracycline Controlled Delivery to Periodontal Pockets: Preliminary Trial in Humans K Schwach-Abdellaoui, PJ Loup, N Vivien-Castioni, A Mombelli, P Baehni, J Barr, J Heller and R Gurny
19. Preformulation Development of Recombinant Pegylated Staphylokinase SY161 Using Statistical Design Frank Bedu-Addo, Randall Moreadith and Siddharth J. Advant
18. Model System to Study Classical Nuclear Export Signals Charu Kanwal, Henan Li and Carol S. Lim
17. Comparison of the Formulation Requirements of Dosator and Dosing Disc Automatic Capsule Filling Machines Pavan K. Heda, Kapiamba Muteba and Larry L. Augsburger
16. The Effect of AlkylpolyglycosideSurfactants on the Crystallization of Spray-Dried Salbutamol Sulphate: a GravimetricNear-Infrared Spectroscopy Study Angela Columbano, Graham Buckton and Philip Wikeley
15. Cloning and Characterization of the Rat Multidrug Resistance-Associated Protein 1 Ziping Yang, Cheryl Li, Danny Shen and Rodney Ho
14. Role of MRP4 and MRP5 in Biology and Chemotherapy
Janardhan Sampath, Masashi Adachi, Sigrid Hatse, Lieve Naesens, Jan Balzarini, Robin Flatley, Larry Matherly and John Schuetz
13. Aerosolization of Lipoplexes Using AERx® Pulmonary Delivery System Deepa Deshpande, James Blanchard, Sudarshan Srinivasan, Dallas Fairbanks, Jun Fujimoto, Teiji Sawa, Jeanine Wiener-Kronish, Hans Schreier and Igor Gonda
12. Transfection Efficiency and Toxicity of Polyethylenimine in Differentiated Calu-3 and Nondifferentiated COS-1 Cell Cultures Bogdan I. Florea, Clare Meaney, Hans E. Junginger and Gerrit Borchard
11. Influence of Fluoxetine on Olanzapine Pharmacokinetics Denis Gossen, Jean-Marie de Suray, Francois Vandenhende, Claude Onkelinx and Diamon Gangji
10. cDNA Microarray Analysis of Vascular Gene Expression After Nitric Oxide Donor Infusions in Rats: Implications for Nitrate Tolerance Mechanisms Ellen Q. Wang, Woo-In Lee, Daniel Brazeau and Ho-Leung Fung
9. Is Antisense an Appropriate Nomenclature or Design for Oligodeoxynucleotides Aimed at the Inhibition of HIV-1 Replication? Carole Lavigne, Jocelyn Yelle, Gilles Sauve, and Alain R. Thierry
8. Pharmacologic and Pharmacokinetic Profile of Repifermin (KGF-2) in Monkeys and Comparative Pharmacokinetics in Humans Cynthia Sung, Tom J. Parry, Todd A. Riccobene, Angela Mahoney, Viktor Roschke, James Murray, Mi Li Gu, Jeffrey K. Glenn, Florence Caputo, Cindy Farman and Daniel J. Odenheimer
7. Assuring Quality and Performance of Sustained and Controlled Release Parenterals: Workshop Report Diane J. Burgess, Ajaz S. Hussain, Thomas S. Ingallinera and Mei-Ling Chen
6. Novel System to Investigate the Effects of Inhaled Volume and Rates of Rise in Simulated Inspiratory Air Flow on Fine Particle Output From a Dry Powder Inhaler Varsha Chavan and Richard Dalby
5. Pharmacogenomics: The Implementation Phase Wolfgang Sadee
4. Protein Binding Predictions in Infants Patrick J. McNamara and Jane Alcorn
3. Application of Confocal Laser Scanning Microscopy in Characterization of Chemical Enhancers in Drug-in-Adhesive Transdermal Patches Michael H. Qvist, Ulla Hoeck, Bo Kreilgaard, Flemming Madsen, Lars Hovgaard, and Sven Frokjaer
2. Ocular Tolerance of Absorption Enhancers in Ophthalmic Preparations Pascal Furrer, Joachim Michael Mayer, Bernard Plazonnet and Robert Gurny
1. Evaluation of USP Apparatus 3 for Dissolution Testing of Immediate-Release Products Lawrence X. Yu, Jin T. Wang and Ajaz S. Hussain
34. Delivery of Antibiotics to the Eye Using a Positively Charged Polysaccharide as Vehicle O. Felt, V. Baeyens, P. Buri and R. Gurny
33. A National Survey of U.S. Pharmacists in 2000: Assessing Nonresponse Bias of a Survey Methodology David A. Mott, Craig A. Pedersen, William R. Doucette, Caroline A. Gaither and Jon C. Schommer
32. The Cytoplasmic Escape and Nuclear Accumulation of Endocytosed and Microinjected HPMA Copolymers and a Basic Kinetic Study in Hep G2 Cells Keith D. Jensen, Pavla Kopeckova, John H.B. Bridge and Jindrich Kopecek
31. Single Nucleotide Polymorphisms of the Human M1 Muscarinic Acetylcholine Receptor Gene Julie L. Lucas, Joseph A. DeYoung and Wolfgang Sadee
30. Receptor Binding Studies of Soft Anticholinergic Agents Fenglei Huang, Peter Buchwald, Clinton E. Browne, Hassan H. Farag, Whei-Mei Wu, Fubao Ji, Guenther Hochhaus and Nicholas Bodor
29. Allometric Scaling of Xenobiotic Clearance: Uncertainty versus Universality
Teh-Min Hu and William L. Hayton
28. Electronic and Resonance Effects on the Ionization of Structural Analogues of Efavirenz Shelly R. Rabel, Mona Patel, Sophie Sun and Michael B. Maurin
27. Skeletal Effects of Parathyroid Hormone (1-34) in Ovariectomized Rats With or Without Concurrent Administration of Salmon Calcitonin Patrick P. DeLuca and Bhas A. Dani
26. Selected Physical and Chemical Properties of Commercial Hypericum perforatum Extracts Relevant for Formulated Product Quality and Performance Susan H. Kopleman, Agnes NguyenPho, William S. Zito, Fran X. Muller and Larry L. Augsburger
25. Comparison of the Gravimetric, Phenol Red, and 14C-PEG-3350 Methods to Determine Water Absorption in the Rat Single-Pass Intestinal Perfusion Model Steven C. Sutton, M.T.S. Rinaldi and K.E. Vukovinsky
24. Influence of Drug Release Properties of Conventional Solid Dosage Forms on the Systemic Exposure of Highly Soluble Drugs Lawrence X. Yu, Christopher D. Ellison, Dale P. Conner, Larry J. Lesko and Ajaz S. Hussain
23. Use of FT-NIR Transmission Spectroscopy for the Quantitative Analysis of an Active Ingredient in a Translucent Pharmaceutical Topical Gel Formulation Mark S. Kemper, Edgar J. Magnuson, Stephen R. Lowry, William J. McCarthy, Napasinee Aksornkoae, D. Christopher Watts, James R. Johnson and Atul J. Shukla
22. Genetic Variations in Human G Protein-Coupled Receptors: Implications for Drug Therapy Wolfgang Sadee, Elen Hoeg, Julie Lucas and Danxin Wang
21. DNA/polyethylenimine transfection particles: Influence of ligands, polymer size, and PEGylation on internalization and gene expression Manfred Ogris, Peter Steinlein, Sebastian Carotta, Sylvia Brunner and Ernst Wagner
20. Comparative Evaluation of Tableting Compression Behaviors by Methods of Internal and External Lubricant Addition: Inhibition of Enzymatic Activity of Trypsin Preparation by Using External Lubricant Addition During the Tableting Compression Process Makoto Otsuka, Mitsuyo Sato and Yoshihisa Matsuda
19. Low Molecular Weight Protamine as Nontoxic Heparin/Low Molecular Weight Heparin Antidote (III): Preliminary In Vivo Evaluation of Efficacy and Toxicity Using a Canine Model Lai Ming Lee, Li-Chien Chang, Shirley Wrobleski, Thomas W. Wakefield, and Victor C. Yang
18.Low Molecular Weight Protamine (LMWP)as Nontoxic Heparin/Low Molecular Weight Heparin Antidote (II): In Vitro Evaluation of Efficacy and Toxicity Li-Chien Chang, Jun Feng Liang, Hsiao-Feng Lee, Lai Ming Lee, and Victor C. Yang
17. Low Molecular Weight Protamine (LMWP) as Nontoxic Heparin/Low Molecular Weight Heparin Antidote (I): Preparation and Characterization Li-Chien Chang, Hsiao-Feng Lee, ZhiQiang Yang, and Victor C. Yang
16. Three-Dimensional Structure of Fibrolase, the Fibrinolytic Enzyme from Southern Copperhead Venom, Modeled from the X-Ray Structure of Adamalysin II and Atrolysin C Michael B. Bolger, Steve Swenson, and Francis S. Markland, Jr.
|