Table of Contents

Original Research Articles

10.Comparisons of pKa and Log P Values of Some Carboxylic and Phosphonic Acids: Synthesis and Measurement
Robert G. Franz

11.Preparation and Characterization of Gelatin Surface Modified PLGA Microspheres
M. Jamie Tsung and Diane J. Burgess

12.Evolutionary Relationships Among G Protein-Coupled Receptors Using a Clustered Database Approach
Richard C. Graul and Wolfgang Sadée

13. Visualization of the Lipid Barrier and Measurement of Lipid Pathlength in Human Stratum Corneum
Priya S. Talreja, Nancy K. Kleene, William L. Pickens, Tsuo-Feng Wang, and Gerald B. Kasting.

14. Study of Crystallization of Endogenous Surfactant in Eudragit NE30D-Free Films and Its Influence on Drug-Release Properties of Controlled-Release Diphenhydramine HCl Pellets Coated with Eudragit NE30D
Angela Y. Lin, Nouman A. Muhammad, David Pope, and Larry L. Augsburger.

15. Time- and Concentration-Dependent Penetration of Doxorubicin in Prostate Tumors
Jenny H. Zheng, Chiung-Tong Chen, Jessie L.-S. Au, and M. Guill Wientjes

16. Three-Dimensional Structure of Fibrolase, the Fibrinolytic Enzyme from Southern Copperhead Venom, Modeled from the X-Ray Structure of Adamalysin II and Atrolysin C
Michael B. Bolger, Steve Swenson, and Francis S. Markland, Jr.