What is EMMS?
The Economic, Marketing, and Management Sciences (EMMS) Section of AAPS
represents an opportunity for pharmaceutical scientists in the EMMS field to
join with other pharmaceutical scientists of all disciplines in advancing
innovative and progressive pharmaceutical therapies. Public policy and
scientific agendas in the interest of patient well-being and scientific
advancement are explored and nurtured through the Section's programming.
Emphasis is placed on economic and policy environment with focused attention on
the marketing and management aspects of pharmaceuticals. Members of the
Section bring the perspectives of the social sciences to the discussions and
deliberations of the Association. The Section's primary functions are: (1) to
stimulate research in areas of economic and policy interests to the
pharmaceutical sciences; (2) to serve as a forum and conduit for distribution
of information; and, (3) to promote and support intellectual and professional
growth.
EMMS Perspectives
by William McGhon, Ph.D.; Ron Corey, Ph.D., Jon Schommer, Ph.D.; Craig
Pedersen, Ph.D.; and Prosonno Gore, Ph.D.
The Economic, Marketing and Management Sciences (EMMS) Section is considered by
some to be the "business end" and "value-added" component of the various AAPS
scientific academies. With concerns about rising drug and health care costs,
EMMS members are conducting important research to help us all understand how to
provide quality health reasonable cost.. The Economic Sciences members conduct
pharmacoeconomic analyses, health economic studies, and budget impact analyse
for medical therapies and pharmacy services. Those involved in the Marketing
Sciences, conduct marketing research, focus groups, and survey research to
assess patient needs for new interventions and satisfaction with current
products. In the Management Sciences, our members examine the principles of
strategic planning, finance, accounting and organizational behavior to improve
the operation and balance sheets of pharmacies and firms.
For the benefits of the non-EMMS member, we provide a brief look at the
exciting i orld of Economic Science. There are expanding
developments in the evolution of pharmacoeconomic tools to assist
decision-makers and managers in finding economically sound ways to advance
patient care. The general discipline of pharmacoeconomics involves
methodologies to evaluate the input and outcomes of health systems and
services. There are methodologies used to evaluate the economic decisions in
today's health cart, system. A few are Listed in Table I.
One of the older tools is cost benefit analysis (CBA) which requires inputs and
patient outcomes to be translated into monetary,-te .,.This remains difficult,
as one must cost the value of pain, or life itself. Although it also requires
inputs in monetary terms, cost utility analysis (CUA) is becoming a more
popular method because it allows dollars for input and patient preferences for
outputs. Cost effectiveness nd cost minimization are the, most popular methods
to evaluate new drugs in the same disease area.
Quality of Life (QOL) is a fast-growing research area and an increasing number
of QOL studies are being conducted to demonstrate potential differences between
products. Decision analysis is a sophisticated methodology that often involves
complex mathematical and statistical models to examine therapy options and
patient outcomes over time.
Table 1. Pharmacoeconomic/Outcomes Research Study Methods
|
METHOD
|
DESCRIPTION
|
USE
|
Cost Benefit Analysis
|
Costs and benefits
expressed in dollars
|
Rarely used today,
too difficult to cost life
|
|
Cost Minimization Analysis
|
Assume equal efficacy,
inputs in dollars,
|
#1 method used in
me-too cases
|
|
Cost Effectiveness Analysis
|
Costs in dollars, effectiveness
in non-monetary value,
|
Most widely used to evaluate
new drugs in same class/disease
|
|
Cost Utility Analysis
|
Costs in dollars, utility a
measurement of patient preference
|
Used to measure across
therapeutics areas/diseases
|
|
Quality of Life Analysis
|
Usually measured by patient survey
|
Expressed as relative number
|
|
Decision Analysis
|
Mathematical Models of decisions
under uncertainty
|
Decision trees used to document
treatment pathways and costs
|
There are many challenges in the evolution of economic methods. A major issue
is the need to specify the budget impact and perspectives of the different
audiences affected by an evaluation. Appropriate alternative therapies are
also debated, since comparison of all therapies would be financially
prohibitive. Effectiveness versus efficacy is, debated, because the efficacy
from a randomized-controtted clinical trial May not be reflected in the "real
world" cost impact of a new therapy once a drug is used in general clinical
practice where we are concerned with effectiveness.
In pharmacoeconomics and outcomes research, we are learning that we must focus
on the patients total health status, not just the tab test values. We are
learning that we must adjust for patient differences in demo graphics,
compliance, severity of illness, and co-morbidities. Whenever possible we
should include in our analyses patient utilities and the perspectives of all
parties, including consumers, providers, employers, and governments.
In the future, we will all no-doubt increasing public demand for more
cost effective health care, and we will all be affected by the puzzle of how to
pa for high quality health care and the new breakthrough medicines. It is
expected that we will hear more demands by employers and insurers to "pay for
outcomes." EMMS members and methodologies wit[ be at the forefront of solutions
to these pressing problems.
|