| By Michael
Levin, Ph.D.
Metropolitan Computing Corporation
East Hanover, NJ
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| Technical Platform
and Requirements: This
79-minute
course is contained within a standard CD-ROM. Requirements include a 486 or faster PC
running Windows 95 or 98, a CD-ROM player, sound card, and speakers. Included on the
disk is a copy of PowerPoint 97 Viewer, which is required to view the course content, and
which must be installed in the default directory in order to properly utilize the
menu-driven program.
|
| Who Should
Participate: This
course is designed for formulation scientists, scale-up engineers, and
general tableting personnel who would like to expand their
understanding of the reasons behind various formulation development
and scale-up problems and to investigate the practical solutions to
such problems.
|
SPECIAL FEATURES
| | 1.5 contact hours (0.15 CEU) will be awarded for successful completion of
multiple choice test (ACPE number: 073-999-00-008-HO4) Extensive references in convenient hard-copy format.
|
| About
the Course:
As formulations are developed and then
moved from small-scale research presses to high-speed production machines,
instrumentation provides vital data for product and process optimization.
Potential scale-up problems can be eliminated by proper use of
sensor derived information and by simulation of production conditions in
the formulation development lab. This course will cover such topics as R&D
grade instrumentation, data acquisition basics, calibration, formulation
optimization, speed dependent characteristics of tableting and scale-up
factors, dwell time comparisons, use of
hydraulic and mechanical compaction simulators, press troubleshooting, and tablet weight control.
Course Outline:
This course will expand on Dr.
Levin’s Arden House presentation and will include the following topics:
Formulation optimization and
fingerprinting
Scale-up factors:p>
Tablet press simulation
Press troubleshooting:p>
Instrumentation for tablet weight control
Presenter Bio:Dr. Michael Levin is the President of
Metropolitan Computing Corporation (MCC) specializing in analytical instrumentation and
data acquisition systems for tablet presses, mixers, roller compactors and other
equipment. Prior to forming MCC in 1985, he has been a consultant to such pharmaceutical
companies as Merck, Sandoz, and Warner-Lambert. He received his Ph.D. in
Biomathematics
(1980) from University of Washington in Seattle. He is a member of the AAPS, ISPE, and
BMES.
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